Post-treatment tumor immune microenvironment and the dual role of myeloid-derived suppressor cells (MDSCs) in cancer progression and therapeutic resistance

Key Points

• Tumor microenvironment influences therapeutic resistance, highlighting its critical role.
• Myeloid-derived suppressor cells exhibit both supportive and suppressive effects on cancer progression.
• The study utilizes immune profiling to assess post-treatment changes in the tumor microenvironment.
• Addressing MDSC dynamics may offer new strategies for enhancing cancer therapy effectiveness.