MiRNA and proteomic profiling of small extracellular vesicles secreted by Toxoplasma gondii cultured with two different human cervical epithelial feeder layers

Key Points

• Extracellular vesicles from Toxoplasma Gondii demonstrate distinct miRNA profiles depending on the epithelial layer cultured.
• miRNA profiling indicates significant variations in expression levels with two human cervical epithelial layers.
• Assessment included both proteomic and miRNA profiling methods to validate findings related to extracellular vesicle secretion.
• Implications of the findings call for further exploration of Toxoplasma Gondii's effects on cervical health.