A Study on the Network Pharmacology of HQGZWWT that Prevents CINP by Inhibiting Ferroptosis through Regulation of the P38/c-FOS/NF-kB Pathway | Synapse
March 3, 2026
A Study on the Network Pharmacology of HQGZWWT that Prevents CINP by Inhibiting Ferroptosis through Regulation of the P38/c-FOS/NF-kB Pathway
Key Points
Inhibition of ferroptosis significantly reduces CINP, suggesting potential treatment avenues.
The observed effects are mediated through the modulation of the p38/c-FOS/NF-kB pathway, a critical molecular route.
Analysis of network pharmacology reveals multiple interactions affecting the ferroptosis mechanism.
The findings highlight the importance of targeted therapies in addressing CINP, yet further validation is necessary.