Subgroup-specific predictive biomarkers in peripheral blood lymphocyte subsets for immune checkpoint inhibitor response in advanced esophageal squamous cell carcinoma: a prospective study

Key Points

• Lymphocyte subsets in peripheral blood correlate with ICI efficacy in patients.
• Key evidence shows that specific subsets are associated with better treatment responses and prognosis.
• Analysis in patients with advanced esophageal squamous cell carcinoma highlights important biomarkers.
• Findings suggest lymphocyte profiling could guide effective treatment decisions for ESCC.