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Tafamidis treatment in transthyretin cardiac amyloidosis: A retrospective cohort analysis of outcomes and associated factors | Synapse
March 3, 2026
Tafamidis treatment in transthyretin cardiac amyloidosis: A retrospective cohort analysis of outcomes and associated factors
JK
Johanna Krief
SA
Sylvain Aguilhon
QD
Quentin Delbaere
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Key Points
Tafamidis treatment significantly improves outcomes in transthyretin cardiac amyloidosis patients, even with various associated factors.
Key patient factors such as age and disease severity were evaluated across a cohort of 150 individuals over 5 years.
Analysis of retrospective cohort data highlights the importance of close monitoring of treatment effects and individual variability.
Findings suggest that personalized approaches could enhance treatment efficacy, though external validation is needed.
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Krief et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e38c6e9836116a28a04
https://doi.org/https://doi.org/10.1016/j.acvd.2025.12.010