Quercetin regulates autophagy and attenuates airway inflammation in a murine model of asthma: association with PI3K/Akt/mTOR signaling pathway modulation

Key Points

• Airway inflammation significantly decreases with quercetin treatment in asthmatic mice, promoting lung health.
• The therapeutic effect is linked to modulation of the PI3K/Akt/mTOR signaling pathway, crucial for cellular processes.
• Observational analysis of murine models highlights the importance of quercetin in regulating excessive autophagy.
• These findings support the potential for quercetin as a new treatment option in asthma management.