Differential protein network and biological functions atlas from multi-tissue proteomics in patients with depression

Key Points

• Differential protein networks were characterized in patients with depression, impacting biological functions involved in mood regulation.
• Important findings include unique biological pathways that may serve as potential biomarkers for diagnosing depression.
• Analysis utilized multi-tissue proteomics to investigate protein expressions across various tissues in the patient cohort.
• These discoveries highlight the complexity of depression, indicating the need for further exploration of protein interactions and their roles.