March 3, 2026Open Access

Class-level drug safety surveillance in hospital practice: A pharmacovigilance analysis of 84 therapeutic subclasses from a South Asian tertiary care center

Key Points

Establishes baseline risk estimates for therapeutic subclasses in pharmacovigilance environments, highlighting the need for improved safety monitoring.
Finds that certain drug classes show disproportionately high-risk profiles, indicating areas for deeper investigation and intervention.
Assessment indicates the robustness of the Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) as tools for drug safety evaluation.
Supports the need for enhanced drug safety protocols in developing regions to counteract high-risk drug class effects.

Abstract

This analysis establishes baseline class-level risk estimates in a developing pharmacovigilance environment, identifies disproportionately high-risk drug classes, and supports the robustness of PRR and ROR as complementary screening tools for regional drug safety monitoring.

Class-level drug safety surveillance in hospital practice: A pharmacovigilance analysis of 84 therapeutic subclasses from a South Asian tertiary care center

Key Points

Abstract

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