Intrinsic tumor factors and extrinsic environmental and social exposures contribute to endometrial cancer recurrence patterns

Key Points

• Endometrial cancer recurrence patterns are influenced by both intrinsic tumor factors and extrinsic environmental exposures.
• Significant predictors include tumor-associated bacterial communities and the immune contexture present in tumors.
• The analysis emphasizes the intertwined roles of environmental factors such as air pollution on cancer outcomes.
• Models predicting disease recurrence may need to be more individualized to account for diverse influencing factors.