Immunological outcomes of autologous hematopoietic stem cell transplantation in multiple sclerosis: A scoping review of post-transplant immune recovery patterns

Key Points

• Improved immune recovery is observed following autologous hematopoietic stem cell transplantation in multiple sclerosis patients, enhancing recovery patterns.
• Key evidence shows notable variations in immune reconstitution metrics after transplantation, reflecting patient response and immunity adaptation.
• This scoping review evaluates existing literature to map post-transplant immune recovery patterns, providing clarity on patient outcomes across several studies.
• Findings highlight the need for further research into immune recovery mechanisms post-transplant, as individual responses can vary widely.