Efficient and recyclable halide-bridged dinuclear copper(I) complex, (nBu4N)2Cu2I4- catalyzed greener click reaction for the regio/chemo-selective synthesis of diverse 1,4-disubstituted 1,2,3-triazoles | Synapse
March 3, 2026
Efficient and recyclable halide-bridged dinuclear copper(I) complex, (nBu4N)2Cu2I4- catalyzed greener click reaction for the regio/chemo-selective synthesis of diverse 1,4-disubstituted 1,2,3-triazoles
Key Points
Diverse 1,4-disubstituted 1,2,3-triazoles were synthesized effectively using a copper(I) catalyst.
The regio- and chemo-selective nature of the reaction was demonstrated using stable reagents.
Analysis utilized a halide-bridged dinuclear copper(I) complex under environmentally friendly conditions.
This method may enable more sustainable practices in triazole synthesis, reflecting the need for greener alternatives.