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Boom-Boom Bridging Radiation Prior to Lisocabtagene Maraleucel Clinical Trial: Outcomes By Total Metabolic Tumor Volume | Synapse
March 3, 2026
Boom-Boom Bridging Radiation Prior to Lisocabtagene Maraleucel Clinical Trial: Outcomes By Total Metabolic Tumor Volume
MA
Mohammad Oussama Ali
Key Points
Total metabolic tumor volume significantly influences treatment outcomes, suggesting optimized therapy is needed.
Participants with higher tumor volume show different responses, which may guide patient selection for clinical trials.
Assessment involves metabolic imaging techniques to measure tumor metabolic activity pre-treatment and post-radiation.
Findings highlight the importance of individualized radiation doses based on tumor volume to improve response rates.
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Mohammad Oussama Ali (Sun,) studied this question.
synapsesocial.com/papers/69a7607fc6e9836116a2d48a
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.539
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