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Early Corticosteroid Exposure after BCMA CAR-T in Multiple Myeloma: Dose-Dependent Impact on Outcomes and Toxicities. | Synapse
March 3, 2026
Early Corticosteroid Exposure after BCMA CAR-T in Multiple Myeloma: Dose-Dependent Impact on Outcomes and Toxicities.
CV
Cindy Varga
Levine Cancer Institute
SA
Shebli Atrash
Levine Cancer Institute
DH
Doris K. Hansen
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Key Points
Corticosteroid exposure significantly influences patient outcomes and toxicities associated with BCMA CAR-T therapy.
Higher doses of corticosteroids correlate with increased toxicities, impacting overall treatment effectiveness.
Analysis across multiple centers highlights the need for careful dose management of corticosteroids post-therapy.
Findings suggest that optimizing corticosteroid use could enhance patient safety in multiple myeloma treatment.
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Varga et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760a2c6e9836116a2d947
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.231