Characteristics and outcome of pediatric and adult differentiated thyroid cancer with distant metastases | Synapse
March 3, 2026Open Access
Characteristics and outcome of pediatric and adult differentiated thyroid cancer with distant metastases
Key Points
Adult differentiated thyroid cancer shows a significant mortality rate of 58% over approximately 4.5 years, indicating high risk.
Pediatric differentiated thyroid cancer is often associated with single organ metastasis, yielding a good outcome with rare mortality.
Multi-organ involvement in adult cases leads to progressive disease, making management more challenging.
Differentiation in characteristics and outcomes between age groups underscores the need for tailored treatment approaches.
Abstract
pDM mostly involve single organs and have good outcome and rare mortality. aDM are frequently multi-organ, progressive and associated with high mortality of 58% over about 4.5 years.