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March 3, 2026
C You Later, Endothelial Injury! Low Vitamin C Post-Hematopoietic Cell Transplant Predisposes to Endothelial Injury and Overall Mortality in Children.
BV
Bethany Verkamp
KB
Kylie E Bota
CT
Cynthia B. Taggart
Cincinnati Children's Hospital Medical Center
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Key Points
Children with low vitamin C after hematopoietic cell transplant show a higher risk of endothelial injury and overall mortality.
Mortality rates were noted to be significantly increased due to oxidative stress linked to low vitamin C levels after transplant.
Observational analysis highlights the connection between insufficient vitamin C and adverse health outcomes post-transplant in young patients.
Findings underscore the importance of monitoring vitamin C levels to potentially reduce mortality risk in this vulnerable population.
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Verkamp et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760b2c6e9836116a2db11
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.878
C You Later, Endothelial Injury! Low Vitamin C Post-Hematopoietic Cell Transplant Predisposes to Endothelial Injury and Overall Mortality in Children. | Synapse