Loss of Triggering Receptor Expressed on Myeloid Cells 2 Impairs Microglial Function and Exacerbates Retinal Neurodegeneration in Glaucoma

Key Points

• Microglial dysfunction is linked to increased retinal neurodegeneration in glaucoma cases.
• The loss of triggering receptor expressed on myeloid cells 2 significantly impairs microglial function and worsens retinal health.
• Observational analysis highlights the role of inflammation in retinal degeneration within glaucoma pathology.
• These findings suggest potential therapeutic targets to address synaptic damage in glaucoma.