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Impact of Obesity on GVHD Following Post-Transplantation Cyclophosphamide in Patients Undergoing Allogeneic Hematopoietic Cell Transplant | Synapse
March 3, 2026
Impact of Obesity on GVHD Following Post-Transplantation Cyclophosphamide in Patients Undergoing Allogeneic Hematopoietic Cell Transplant
NA
Naveed J. Ali
AH
Alycia Hatashima
University of Washington
XF
Xinyi Fan
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Key Points
Obesity significantly raises the risk of graft-versus-host disease (GVHD) after transplantation.
Patients with higher body mass indexes may experience more severe immune responses post-transplant.
Assessment through a detailed investigation involving multiple centers and patient records unveiled key patterns in outcomes.
This highlights the importance of considering obesity when predicting GVHD in transplant patients.
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Ali et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760dfc6e9836116a2e078
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.668
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