Shoeblackplant extract–loaded carboxymethyl cellulose/collagen scaffolds seeded with adipose-derived stem cells enhance diabetic wound healing via immunomodulation and angiogenic pathways

Key Points

• Diabetic wound healing improves significantly with the use of Shoeblackplant extract.
• The method utilized scaffolds loaded with carboxymethyl cellulose and collagen, enabling better cell integration.
• Observational analysis revealed that adipose-derived stem cells played a crucial role in immunomodulation and angiogenesis.
• This approach may lead to more effective treatments for patients with diabetic wounds who struggle with healing.