The VAX2-SERPINE1 axis modulates colorectal cancer cell proliferation and apoptosis through WNT/beta-catenin signaling

Key Points

• Colorectal cancer cell proliferation decreases when VAX2 is inhibited, showing a key role in cell growth.
• The VAX2-SERPINE1 axis influences apoptosis through the WNT/beta-catenin signaling pathway in cancer cells.
• Analysis focused on colorectal cancer cells, demonstrating the impact of the VAX2-SERPINE1 interaction on cellular dynamics.
• Findings indicate potential therapeutic targets for improving colorectal cancer treatment strategies.