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Association between serum uric acid levels and osteoporosis risk: evidence from a cross-sectional study and Mendelian randomization analysis | Synapse
March 3, 2026
Association between serum uric acid levels and osteoporosis risk: evidence from a cross-sectional study and Mendelian randomization analysis
QL
Qi-Pei Liu
Guangzhou University of Chinese Medicine
LZ
Lei-Xiao Zhang
Guangzhou University of Chinese Medicine
JL
Jie-Hua Luo
Guangzhou University of Chinese Medicine
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Key Points
Osteoporosis risk is linked to serum uric acid levels, emphasizing its role as a potential biomarker.
The study indicates that individuals with higher uric acid levels have a different osteoporosis risk profile.
Mendelian randomization analysis strengthens the findings, providing genetic support for the association observed.
Understanding this relationship could inform future interventions aiming to reduce osteoporosis incidence.
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Liu et al. (Sat,) studied this question.
synapsesocial.com/papers/69a7614dc6e9836116a2f18e
https://doi.org/https://doi.org/10.1007/s10067-026-07986-3