Short-term linaclotide plus polyethylene glycol in patients at increased risk of inadequate bowel preparation: A randomized, double-blind, multicenter trial | Synapse
March 3, 2026Open Access
Short-term linaclotide plus polyethylene glycol in patients at increased risk of inadequate bowel preparation: A randomized, double-blind, multicenter trial
Key Points
Enhanced bowel preparation noted with the combination of linaclotide and polyethylene glycol, leading to better outcomes.
The study observed a significant improvement, with 75% of participants achieving adequate preparations as compared to previous methods.
Conducted as a randomized double-blind multicenter trial involving diverse patient populations to assess effectiveness across settings.
Findings support the use of these interventions, although multi-center limits may affect generalizability to broader populations.