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Pan-cancer immunogenomics and structure-guided repurposing identify N-Acetyl-L-carnosine as a PAR2 binding modulator | Synapse
March 3, 2026
Pan-cancer immunogenomics and structure-guided repurposing identify N-Acetyl-L-carnosine as a PAR2 binding modulator
CA
Carlton Ranjith Wilson Alphonse
AC
Asha Caroline Cyril
AP
Anagha Parambath
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Key Points
N-acetyl-L-carnosine shows promise as a PAR2 binding modulator, indicating its potential utility in cancer therapies.
The study highlights the integration of immunogenomics with structure-guided repurposing to discover new therapeutic agents.
This analysis emphasizes the relevance of binding modulators in cancer treatment strategies, aiming to enhance immunotherapy efficacy.
Potential applications span multiple cancer types, inviting further investigation into N-acetyl-L-carnosine's benefits and mechanisms.
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Alphonse et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7618ec6e9836116a2f959
https://doi.org/https://doi.org/10.1007/s10787-026-02137-1