Understanding cytotoxicity induction by plumbagin in pancreatic ductal adenocarcinoma using network pharmacology, bioinformatic and in-vitro study | Synapse
March 3, 2026Open Access
Understanding cytotoxicity induction by plumbagin in pancreatic ductal adenocarcinoma using network pharmacology, bioinformatic and in-vitro study
Key Points
Cytotoxicity induction was evident with plumbagin treatment, affecting cancer cell viability significantly.
In vitro findings showed over 70% cytotoxic effects at specific concentrations of plumbagin after 48 hours.
The study employs network pharmacology and bioinformatics to uncover molecular pathways involved in plumbagin's action.
These results highlight plumbagin's potential as a therapeutic agent, warranting further investigation in clinical settings.