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β-defensin1 antimicrobial peptide protects mitochondrial function, DNA integrity and calcium homeostasis in cryopreserved buck spermatozoa | Synapse
March 3, 2026
β-defensin1 antimicrobial peptide protects mitochondrial function, DNA integrity and calcium homeostasis in cryopreserved buck spermatozoa
MK
Manish Kumar
RR
Ravi Ranjan
AB
Alok Bharadwaj
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Key Points
Protection of mitochondrial function occurs in the presence of β-defensin1, highlighting its role as an antimicrobial peptide.
Maintenance of DNA integrity is improved when β-defensin1 is utilized, indicating its protective properties.
Assessment involved cryopreserved buck spermatozoa to analyze the effects of β-defensin1 on cellular functions.
Findings support the potential of β-defensin1 in enhancing sperm preservation methods, impacting reproductive technologies.
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Kumar et al. (Wed,) studied this question.
synapsesocial.com/papers/69a761efc6e9836116a3005d
https://doi.org/https://doi.org/10.1016/j.smallrumres.2026.107735