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Modified natural versus natural cycle for endometrial preparation in frozen embryo transfer: a meta-analysis | Synapse
March 3, 2026
Modified natural versus natural cycle for endometrial preparation in frozen embryo transfer: a meta-analysis
CV
Christos Venetis
Aristotle University of Thessaloniki
KK
Kokkoni I Kiose
Aristotle University of Thessaloniki
MA
Maria Apostolidou
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Key Points
Modified natural cycle shows improved outcomes compared to natural cycle for frozen embryo transfer.
The analysis includes 15 studies with over 1,000 cycles evaluated for effectiveness.
Meta-analysis of results indicates specific benefits in success rates for modified natural methods.
Findings may impact best practices in fertility clinics for embryo transfer preparations.
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Venetis et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76220c6e9836116a3034d
https://doi.org/https://doi.org/10.1016/j.fertnstert.2026.02.021
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