Genetic and epidemiological patterns of primary immunodeficiency diseases in Eastern Iranian patients

Key Points

• Primary immunodeficiency diseases show distinct genetic and epidemiological patterns among Eastern Iranian patients, with some cases linked to specific genetic markers.
• Significant prevalence rates of primary immunodeficiency diseases among individuals in Eastern Iran highlight the need for targeted diagnostics.
• Genetic analysis in this observational study reveals inherited patterns, including both specific mutations and environmental factors influencing disease presentation.
• Findings suggest a regional focus on understanding primary immunodeficiency diseases, calling for more research and broader genetic screening efforts.