Testing equivalence for three-arm trials with multinomial outcomes

Key Points

• Equivalence testing for statistical methods indicates a viable approach for three-arm trials with multinomial outcomes.
• A defined significance threshold of 0.05 is used to evaluate whether the results meet equivalence criteria.
• The approach can facilitate better comparisons among various interventions tested in clinical scenarios.
• These findings highlight the need for refined methods in trial design to enhance robustness and interpretation.