Synthesis, structural characterization, and anticancer potential of a hydrazone-based schiff base oxovanadium(IV) Complex targeting the HPV-18 E6 PDZ domain

Key Points

• The hydrazone-based oxovanadium complex demonstrates significant anticancer activity against HPV-18.
• Experimental findings show a 75% inhibition of cancer cell proliferation in vitro.
• Analysis incorporates structural characterization and interaction studies of the complex.
• Supports further investigation into targeted early-stage cancer therapy, especially for HPV-related cancers.