Highly efficient gene editing via targeted Cas9 insertion into chicken housekeeping gene

Key Points

• Gene editing efficiency increased through targeted insertion of Cas9 into a housekeeping gene, enhancing precision.
• The analysis utilized genetically modified chickens to showcase the potential of this molecular biology technique.
• Laboratory experiments confirmed successful integration and function of the edited gene at a molecular level.
• This progress in genome editing may enable new therapeutic options, although broader applications require further investigation.