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HSF4 alleviates ferroptosis in colorectal cancer through transcriptional regulation of MBOAT1/2 | Synapse
March 3, 2026
HSF4 alleviates ferroptosis in colorectal cancer through transcriptional regulation of MBOAT1/2
KY
Kelin Yue
HW
Haolin Wu
KL
Kexin Li
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Key Points
Ferroptosis is alleviated in colorectal cancer through the action of HSF4.
HSF4 significantly regulates the genes MBOAT1 and MBOAT2, impacting tumor behavior.
Analysis employed for understanding the role of transcriptional regulation in cancer.
Potential therapeutic implications are suggested for targeting HSF4 in cancer treatment.
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Cite This Study
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Yue et al. (Mon,) studied this question.
synapsesocial.com/papers/69a7659dbadf0bb9e87d9bee
https://doi.org/https://doi.org/10.1007/s10142-026-01822-2