Ultrasensitive detection of gastric cancer biomarker using tetrahedral DNA nanostructure-functionalized floating-gate carbon nanotube field-effect transistor biosensor

Key Points

• Detection of gastric cancer biomarkers shows improved sensitivity and specificity using the developed biosensor.
• The biosensor achieved detection limits as low as 0.1 pg/mL for specific biomarkers, indicating high sensitivity.
• Assessment using a tetrahedral DNA nanostructure to enhance the biosensor's performance in detecting gastric cancer biomarkers.
• These findings support the potential of using advanced nanostructures for early cancer detection and diagnosis.