Association between chronic stress-related amygdala metabolic activity and distant metastasis in colorectal cancer

Key Points

• Distant metastasis was found to be independently associated with elevated amygdala metabolic activity, indicating a potential risk factor.
• Amygdala metabolic activity measured by ¹⁸F-FDG PET/CT may serve as a novel imaging biomarker for colorectal cancer.
• The study investigates how chronic stress affects amygdala metabolic activity and the progression of colorectal cancer metastasis.
• Findings highlight the need for further research on stress mechanisms in cancer, as understanding these could improve patient outcomes.