Association of apolipoprotein E gene polymorphisms with risk of coronary artery disease in a Han Chinese population at middle and high altitude in China | Synapse
March 3, 2026Open Access
Association of apolipoprotein E gene polymorphisms with risk of coronary artery disease in a Han Chinese population at middle and high altitude in China
Key Points
The APOE ε3ε4 genotype is linked with higher risk of coronary artery disease.
Individuals with this genotype show an increased likelihood of CAD onset at middle and high altitudes.
The analysis emphasizes genetic factors in coronary artery disease risk management.
Findings support the notion that genetic predisposition plays a role in CAD risk among specific populations.
Abstract
These findings validated that the APOE gene's ε3ε4 genotype is a potential predictor for CAD onset in Han Chinese individuals at middle and high altitudes.