Pathological effects of diabetic mice with Helicobacter pylori infection

Key Points

• H. pylori infection significantly exacerbates stomach, liver, and kidney damage in diabetic mice, indicating serious health implications.
• Colonization time of H. pylori is significantly prolonged in the stomach of diabetic mice, leading to increased organ damage.
• The assessment involved a STZ-induced diabetic mouse model, which reflects real-world complications in diabetes and infections.
• These findings highlight the need for monitoring gastrointestinal health in diabetic individuals infected with H. pylori.