March 3, 2026Open Access

A 10-year registry-based retrospective study of cutaneous Leishmaniasis in Mashhad, northeastern Iran: Demographic, clinical, and therapeutic profiles of 1537 cases

Key Points

Cutaneous leishmaniasis remains a critical public health issue, impacting local populations significantly.
Findings indicate that the disease burden may be underestimated, particularly due to climatic and demographic factors.
This observational analysis examines treatment outcomes among 1537 cases observed over ten years.
Strengthened surveillance and public awareness are essential for effective disease management and control programs.

Abstract

CL remains a major public health concern in Mashhad, Iran. Despite encouraging cure rates, the true disease burden is likely underestimated. Demographic and climatic factors influence its distribution. Longitudinal and clinical studies are warranted to better understand treatment outcomes. Strengthened surveillance, public awareness, and coordinated control programs are crucial for sustainable disease management.

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