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Relapse of minimal change nephrotic syndrome after initiation of sulfamethoxazole–trimethoprim combination therapy: a case report | Synapse
March 3, 2026
Open Access
Relapse of minimal change nephrotic syndrome after initiation of sulfamethoxazole–trimethoprim combination therapy: a case report
TS
Takuya Sugiura
Japanese Red Cross Nagoya Daiichi Hospital
SI
Shun Ito
Nihon University
NS
Naohiro Sakaguchi
Japanese Red Cross Nagoya Daiichi Hospital
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Key Points
Relapse of minimal change nephrotic syndrome occurred after initiating therapy.
The patient showed signs of a flare-up within a month of starting treatment.
Observation documented the effects of sulfamethoxazole and trimethoprim on kidney function.
This case underlines the need for careful management in nephrology when prescribing antibiotics.
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Sugiura et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76784badf0bb9e87e13b7
https://doi.org/https://doi.org/10.1007/s13730-025-01082-2
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