Metabolomics-based investigation of PFOS-induced molecular perturbations across multiple rat organs

Key Points

• PFOS exposure results in significant molecular perturbations in various rat organs, indicating potential health risks.
• The study identifies key biomarkers of exposure and response related to metabolomics, enabling better understanding of toxicity.
• Assessment employed comprehensive metabolomic profiling to analyze organ-specific changes, confirming the broad effects of PFOS.
• Findings highlight the need for further exploration into the long-term health impacts of PFOS on organ function and metabolism.