Heavy and trace metals toxicity implications in the breakdown of cellular homeostasis: A risk factor for rheumatoid arthritis pathogenesis

Key Points

• Cellular homeostasis breakdown significantly correlates with increased risk of rheumatoid arthritis.
• Toxic metals, including heavy and trace variants, can disrupt immune response and promote inflammation.
• Analysis of immune responses to toxic exposure highlights the link between metal toxicity and oxidative stress.
• This study suggests that monitoring toxic metal exposure may be crucial in understanding rheumatoid arthritis risks.