Unraveling the impact of chemoradiotherapy on hematopoietic function in cancer patients: a metabolomics-driven mechanistic investigation

Key Points

• Hematopoietic function changes significantly post-chemoradiotherapy, influencing patient recovery.
• Key biomarkers of hematopoietic function were identified, emphasizing the role of specific cancer metabolites.
• Metabolomics-driven investigation assessed cellular changes linked to chemoradiotherapy effects.
• Study highlights how altered cell signaling pathways can impact treatment efficacy and patient health.