METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers

Key Points

• Identification of functional m6A sites in various cancers indicates their role in tumor biology.
• Using METTL3-based epitranscriptomic editing, 15 specific m6A sites were pinpointed as significant.
• Screening method revealed critical insights into m6A modifications across different cancer types.
• These findings support exploring m6A sites as potential targets for cancer therapies.