Virtual myocardial blood flow and flow reserve from static PET imaging using artificial intelligence

Key Points

• Virtual stress myocardial blood flow and flow reserve assessments are feasible, enhancing diagnostic capabilities.
• AI was used to assess flow metrics from static PET images, without the need for dynamic acquisitions.
• The analysis supports broader clinical applicability of flow quantification methods across diverse patient populations.
• This approach may simplify clinical workflows, but external validation is necessary for widespread implementation.