What question did this study set out to answer?

This research focuses on developing a nanocellulose platform with dual functionalities for drug delivery.

March 5, 2026Biomaterials Science1 citationsOpen Access

Nanocellulose with Dual Carboxy and Aldehyde Functionality: a Modular Platform for Hydrogel Formation and Sustained Drug Release

EBEmanuela BuaResearch Centre for Cereal and Industrial Crops CSChiara SpanuResearch Centre for Cereal and Industrial Crops GIGiovanni InzalacoIstituto per lo Studio e la Prevenzione Oncologica

Key Points

This research focuses on developing a nanocellulose platform with dual functionalities for drug delivery.
Synthesis of nanocellulose with carboxy and aldehyde functionalities.
Evaluation of hydrogel formation and characteristics.
Assessment of drug release kinetics under simulated conditions.
Hydrogel formation demonstrated significant control over drug release rates.
Nanocellulose showed high biocompatibility with soft tissue.
Tunable porosity led to optimized drug delivery systems.

Abstract

Nanocellulose-based hydrogels hold great promise for biomedical applications, particularly as localized drug delivery systems, due to their biocompatibility, tuneable porosity, and soft-tissue mimicking properties. However, most reported systems rely on...

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