Neuroprotective effect of juglone against 6-OHDA-induced neurotoxicity in PC12 cells

Key Points

• This research aims to evaluate the neuroprotective effects of juglone on neurotoxicity induced by 6-OHDA in PC12 cells.
• Utilized PC12 cells to model neurotoxicity.
• Administered juglone to assess protective effects.
• Measured cell viability and neurotoxic markers.
• Juglone treatment significantly increased cell viability.
• Juglone reduced markers of neurotoxicity in treated cells.
• Demonstrated a dose-dependent protective effect of juglone.