What question did this study set out to answer?

To highlight the presentation of chronic myeloid leukaemia as asymptomatic leukocytosis during pregnancy.

March 6, 2026BMJ Case Reports0 citations

Chronic myeloid leukaemia (CML) presenting as asymptomatic leukocytosis in pregnancy

SKSowmya KoteshwaraJSS Academy of Higher Education and Research KGKrishna Madhuri GaddeJSS Academy of Higher Education and Research MRMahesh RajashekaraiahJSS Academy of Higher Education and Research

Key Points

To highlight the presentation of chronic myeloid leukaemia as asymptomatic leukocytosis during pregnancy.
Case report of a woman in her early 30s with marked leukocytosis at term
Assessment of leukocyte counts to rule out underlying causes
Conservative management through delivery
Patient diagnosed with chronic myeloid leukaemia following delivery
Leukocytosis presented asymptomatically
Emphasis on the need for monitoring leukocyte counts in pregnant individuals

Abstract

Although mild leukocytosis is common in pregnancy, markedly elevated counts warrant prompt evaluation to exclude pathological causes such as infections and leukaemia. Chronic myeloid leukaemia (CML) is a chronic myeloproliferative condition increasingly being seen in younger age groups. Here we report a woman in her early 30s with asymptomatic marked leukocytosis at term, subsequently diagnosed with CML. As she was near term, she was managed conservatively through delivery before initiation of definitive therapy postpartum. This case underscores the importance of baseline and serial leucocyte monitoring in pregnancy and highlights the unique therapeutic challenges of managing CML during pregnancy.

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