Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis

Key Points

• The research aims to determine the incidence of acne in patients with inflammatory bowel disease (IBD) treated with Janus kinase (JAK) inhibitors.
• Conducted a systematic review and meta-analysis
• Included studies reporting acne occurrences in IBD patients
• Analyzed data on different subpopulations, including pediatrics and treatment phases
• Acne incidence was significantly higher in patients treated with upadacitinib
• The pediatric population displayed a particularly high incidence of acne
• Higher occurrence of acne was noticed during the induction phase of JAK inhibitor treatment