Association Between Gout and the Risk of Dementia: A Meta-Analysis of Observational Studies and Biological Mechanisms. | Synapse
March 7, 2026
Association Between Gout and the Risk of Dementia: A Meta-Analysis of Observational Studies and Biological Mechanisms.
Key Points
This research aims to understand the relationship between gout and the risk of developing dementia, along with examining underlying biological mechanisms.
Conducted a meta-analysis of observational studies
Assessed the association between gout and dementia risk
Evaluated biological mechanisms linking the two conditions
Findings indicate a significant association between gout and increased dementia risk
Suggests potential biological pathways that may contribute to cognitive decline
Highlights the importance of managing gout in older adults to possibly reduce dementia risk
Abstract
International Platform of Registered Systematic Review and Meta-analysis Protocols INPLASY2025110018; https://doi.org/10.37766/inplasy2025.11.0018.