What does this research mean for the field?

Patients with active inflammatory bowel disease (IBD) experience more severe influenza-related outcomes compared to those with inactive IBD. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

The aim is to compare influenza-related outcomes in patients with active versus inactive inflammatory bowel disease (IBD).

March 8, 2026Open Access

Severe Influenza-Related Outcomes in Patients with Inflammatory Bowel Disease on Immunosuppressive Therapy: A Propensity-Matched Cohort Analysis

Key Points

The aim is to compare influenza-related outcomes in patients with active versus inactive inflammatory bowel disease (IBD).
Conducted a propensity-matched cohort analysis
Included patients with active and inactive IBD
Evaluated severe outcomes related to influenza infection
Analyzed vaccine uptake and respiratory symptom evaluation during flu seasons.
Patients with active IBD faced more severe influenza outcomes than those with inactive IBD
Improvements in vaccine uptake are necessary for better prevention
Prompt evaluation of respiratory symptoms is crucial during influenza seasons.

Abstract

Patients with active IBD had more severe influenza-related outcomes compared with those with inactive IBD. Improving vaccine uptake and prompt evaluation of upper respiratory symptoms during influenza seasons are key to reducing influenza-related risks in immunosuppressed patients with IBD.

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Cite This Study

Eldesouki et al. (Fri,) studied this question.

synapsesocial.com/papers/69ada873bc08abd80d5bb61c https://doi.org/https://doi.org/10.1007/s10620-026-09773-1

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