Persimmon consumption caused excessive anticoagulation in a warfarin-treated patient with mechanical heart valves due to a potential food-drug interaction.
Does persimmon consumption lead to excessive anticoagulation in patients receiving warfarin therapy?
Persimmon consumption should be considered as a potential cause of unexpected excessive anticoagulation in patients on warfarin.
Absolute Event Rate: 0% vs 0%
This case highlights a potential food-drug interaction between persimmons and warfarin leading to excessive anticoagulation. The mechanism may involve more than vitamin K content alone, warranting further investigation. Physicians should consider dietary habits, including local or seasonal foods, in warfarin-treated patients presenting with unexpected coagulation changes.
Kim et al. (Fri,) reported a other. Persimmon consumption caused excessive anticoagulation in a warfarin-treated patient with mechanical heart valves due to a potential food-drug interaction.