Does preexisting right or left ventricular systolic dysfunction affect perioperative outcomes and long-term survival in patients undergoing TAVR?
Right ventricular systolic dysfunction is an independent risk factor for late mortality after TAVR, though perioperative outcomes remain unaffected, supporting TAVR as a preferred therapy in these patients.
Peri-operative mortality and risk of stroke after TAVR are not adversely affected by preexisting RV or LV dysfunction. Long-term survival is impaired in patients with RVSD. RVSD but not LVSD is an independent risk factor for late mortality. TAVR should be the preferred therapy for patients with RVSD and LVSD, especially when patient is suitable for TF.
Griese et al. (Tue,) studied this question.