Endobronchial ultrasound-guided transbronchial needle aspiration successfully diagnosed primary pulmonary leiomyosarcoma in an 82-year-old man with rapid progression and brain metastasis.
EBUS-TBNA is a valuable diagnostic tool for obtaining adequate tissue to definitively diagnose rare pulmonary sarcomas such as primary pulmonary leiomyosarcoma.
Absolute Event Rate: 0% vs 0%
ABSTRACT Primary pulmonary leiomyosarcoma (PPL) is a rare malignant tumour with a poor prognosis, particularly in unresectable cases. We report the case of an 82‐year‐old man who was referred for evaluation of an incidental chest abnormality. Chest computed tomography (CT) revealed a nodule in the left upper lobe and enlargement of the 4L lymph node. An initial bronchoscopic biopsy was inconclusive; however, leiomyosarcoma was subsequently diagnosed using endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) of the lymph node. The patient later developed a solitary brain metastasis detected by brain computed tomography and was treated with Gamma Knife radiosurgery, followed by chemotherapy. Despite treatments, the disease progressed rapidly, and the patient died 4 months after the initial diagnosis. This case highlights the diagnostic value of EBUS‐TBNA in obtaining adequate tissue for definitive diagnosis of rare pulmonary sarcomas and illustrates the aggressive clinical course of PPL with brain metastasis.
Yabe et al. (Sun,) reported a other. Endobronchial ultrasound-guided transbronchial needle aspiration successfully diagnosed primary pulmonary leiomyosarcoma in an 82-year-old man with rapid progression and brain metastasis.